School Program

March 23rd – 30th: 1st ISN Latin American School of Advanced Neurochemistry: In vitro and in vivo neurochemical approaches applied to the study of neurodegeneration

Morning
09:00-9:15 Opening of the 1st ISN Latin American School of Advanced Neurochemistry: Neurochemical Cell Interactions: relevance for neurodegeneration. School Directors
9:15-9:45 An overview of CNS neurochemical interactions. F. Dajas
Neuron-Glia Interaction
9:45-10:30 The neuron fate: survival vs death. L. Barbeito
10:30-11:00 Coffee break
11:00- 11:45 Astrocyte biochemistry and physiology. P. Cassina
11:45- 12:30 Gliotransmission through hemichannels. V. Abudara
14:30 Experimental seminars
21:00 Dinner – Restaurant Terruño *

Morning: Oligodendrocytes, Schwann cells and microglia
09:00-10:00Introducing oligodendrocytes. L. Martinez-Palma
10:00-11:00 Schwann cells and myelination. A. Kun - C. Vazquez
11:00-11:30 Coffee break
11:30- 12:30 Microglia: growth, phenotypes and physiological roles during development. M. Mallat/li>
14:30 Presentation of experimental seminars by students (I)
18:00-20:00 OLYMPUS lecture
21:00 Dinner – Restaurant Terruño *

Morning: Glial cells and CNS pathology
09:00-10:00 Role of astrocytes in neurodegeneration. L. Barbeito
10:00-11:00 Astrocytes response to excitotoxicity. F. Gomes
11:00-11:30 Coffee break
11:30- 12:30 Activation of microglia: cellular, molecular and pathophysiological aspects. M. Mallat
14:30 Experimental seminars
21:00 Dinner – Restaurant Terruño *

Approaches to study the neurobiology of disease
09:00-9:45 How to assess glial cell participation in pathology. S. Boillée
09:45-10:30 In vitro and in vivo models to study neurodegeneration. P. Cassina - S. Olivera
10:30-11:00 Coffee break
11:00-11:30 Genomic in neurobiology. J. Sotelo Silveira
11:30-12:00 Demyelinating pathologies: a clinical approach. C. Vazquez - A. Kun
12:00-12:30 The importance of being innervated: the role of nerves in uterine pathology. M. Brauer
14:30 Experimental seminars
Evening: Mini-Symposium: Neurodegeneration and Neuroprotection Club Nuevo Banco Comercial, Sala del Mar * Chairs: P. Cassina, S. Olivera, G. Prunell Participants: J. Sotelo Silveira, J. Segura-Aguilar, S. Boillée, M. Mallat, CM. Troy
21:00 Dinner

Morning: Mechanisms underlying neurodegeneration
09:00-10:00 Neurodegenerative diseases: proposed pathological mechanisms. J. Segura-Aguilar
10:00-11:00 Different pathways leading to neuronal death. CM. Troy
11:00-11:30 Coffee break
11:30-12:30 Iron homeostasis, oxidative stress and neurodegeneration. MT. Nuñez
14:30 Experimental seminars
21:00 Dinner – Restaurant Terruño *

Morning: Parkinson disease as a prototypic neurodegenerative disease
09:00-10:00 Introducing to Parkinson disease. J. Segura-Aguilar
10:00-11:00 Iron accumulation in the progress of Parkinson disease. MT. Nuñez
11:00-11:30 Coffee break
11:30-12:30 Protection mediated by nicotinic receptors in Parkinson Disease. F. Dajas - JA. Abin-Carriquiry
Afternoon Student oral presentation (part II)
Evening: ISN School Closing Museo Municipal de Bellas Artes "Juan Manuel Blanes" *
20:00 Closing Ceremony

Morning: State of the art of neuroprotective approaches Instituto Pasteur de Montevideo *
08:30-9:30 Cre/Lox technology. S. Boillée
09:30-10:15 Gene therapy and neurodegeneration. H. Peluffo
10:15-10:45 Coffee break
10:45-11:45 siRNA delivery to neurons. CM. Troy
11:45-12:30 Visit to the Institut Pasteur Montevideo laboratories *
14:30 Experimental seminars